{"created":"2023-06-19T08:25:11.932621+00:00","id":28,"links":{},"metadata":{"_buckets":{"deposit":"37b3ff5b-3011-46d8-88b9-63f5835b6102"},"_deposit":{"created_by":18,"id":"28","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"28"},"status":"published"},"_oai":{"id":"oai:hokuriku.repo.nii.ac.jp:00000028","sets":["29:51"]},"author_link":["108"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"33","bibliographicPageEnd":"15","bibliographicPageStart":"11","bibliographic_titles":[{"bibliographic_title":"北陸大学紀要"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ニトロプルシドナトリウム(SNP)注の無菌性を証明し、適した無菌試験法を検討した。SNP注は、通常の無菌試験では濁り現象を生じ、さらに高圧蒸気で滅菌後でも濁り現象を生じた。しかし、メンブランフィルター法で細菌を濾過捕集する方法では濁り現象は見られず、細菌の発育は認めなかった。また、固形培地法でも細菌コロニーの形成は観察しなかった。SNP注の調製における無菌操作法には問題はなく、濁り現象が起こる原因は、SNPとチオグリコール酸培地の成分との関係にあることが推察された。無菌試験用のチオグリコール酸培地、高圧蒸気滅菌法、およびメンブランフィルター法のいずれも問題はなく、固形培地法の有用性も確認した。濁り現象の原因はチオグリコール酸培地中の酵母エキスに含まれる金属イオンと考えられた。SNPと培地の成分とが直接触れることのないメンブランフィルター法によって無菌試験を行うのが適当であると考えられた。","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15066/00000026","subitem_identifier_reg_type":"JaLC"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0387-074X","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤下, 修"}],"nameIdentifiers":[{"nameIdentifier":"108","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000020380933","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-05-15"}],"displaytype":"detail","filename":"yaku2.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"yaku2","url":"https://hokuriku.repo.nii.ac.jp/record/28/files/yaku2.pdf"},"version_id":"c326c262-8d71-4233-b8d6-07dffaee5575"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"*Nitroprusside","subitem_subject_scheme":"Other"},{"subitem_subject":"細菌学的技法","subitem_subject_scheme":"Other"},{"subitem_subject":"比濁法と濁度測定","subitem_subject_scheme":"Other"},{"subitem_subject":"*無菌","subitem_subject_scheme":"Other"},{"subitem_subject":"*液体薬剤","subitem_subject_scheme":"Other"},{"subitem_subject":"高圧蒸気滅菌法","subitem_subject_scheme":"Other"},{"subitem_subject":"*注射剤","subitem_subject_scheme":"Other"},{"subitem_subject":"メンブレンフィルター","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ニトロプルシドナトリウム注射薬の無菌試験法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ニトロプルシドナトリウム注射薬の無菌試験法"}]},"item_type_id":"10002","owner":"18","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-05-15"},"publish_date":"2014-05-15","publish_status":"0","recid":"28","relation_version_is_last":true,"title":["ニトロプルシドナトリウム注射薬の無菌試験法"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-06-19T08:44:07.064074+00:00"}