{"created":"2023-06-19T08:25:35.613850+00:00","id":499,"links":{},"metadata":{"_buckets":{"deposit":"2123b159-a9ff-4d75-9ff8-7e971eab3549"},"_deposit":{"created_by":18,"id":"499","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"499"},"status":"published"},"_oai":{"id":"oai:hokuriku.repo.nii.ac.jp:00000499","sets":["38:143"]},"author_link":["338"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"733","bibliographicPageStart":"730","bibliographicVolumeNumber":"53","bibliographic_titles":[{"bibliographic_title":" Journal of Health Science"},{"bibliographic_title":" Journal of Health Science","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ゲニピンの構造的電気的特性と神経型一酸化窒素合成酵素(nNOS)の重要な補因子であるテトラヒドロビオプリテリン(H4B)やnNOSの阻害物質である4-アミノテトラヒドロビオプテリン(4-amino-H4B)の特性を、コンピューター補助分子モデリング法を用いて比較した。LUMOエネルギー計算に加え、分子モデリング、スーパーインポーズ、ドッキングシミュレーションによる結果は、ゲニピンがH4Bの構造的電気的特性と著しく類似していることを明らかにした。","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"公益社団法人日本薬学会"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1344-9702","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Suzuki, Hirokazu"}],"nameIdentifiers":[{"nameIdentifier":"338","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70257484 ","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70257484 "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-16"}],"displaytype":"detail","filename":"Journal of Health Science  2007.12.pdf","filesize":[{"value":"445.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Journal of Health Science  2007.12","url":"https://hokuriku.repo.nii.ac.jp/record/499/files/Journal of Health Science  2007.12.pdf"},"version_id":"97701435-9b0f-4b3a-8ba8-75af99ae843c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"genipin, tetrahydrobiopterin, 4-aminotetrahydrobiopterin, molecular modeling, neuronal nitric oxide synthase","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Characteristic Properties of Genipin as an Activator in Neuronal Nitric Oxide Synthase","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Characteristic Properties of Genipin as an Activator in Neuronal Nitric Oxide Synthase"},{"subitem_title":"Characteristic Properties of Genipin as an Activator in Neuronal Nitric Oxide Synthase","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"18","path":["143"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-01-18"},"publish_date":"2018-01-18","publish_status":"0","recid":"499","relation_version_is_last":true,"title":["Characteristic Properties of Genipin as an Activator in Neuronal Nitric Oxide Synthase"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-06-19T08:35:09.585839+00:00"}